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Caliper Launches Small Animal Molecular Imaging System Enabling Real-Time Video Observation

Wednesday, September 10, 2008 General News
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HOPKINTON, Mass., Sept. 9 Caliper Life Sciences,Inc. (Nasdaq: CALP), a leading provider of tools and services for drugdiscovery and life sciences research, today introduced the IVIS(R) Kineticpreclinical in vivo imaging system. The system enables researchers tonon-invasively view biological events at the molecular level as they occur inreal-time. The IVIS Kinetic system utilizes the latest developments inultra-high sensitivity scientific cameras to add video capability to thecompany's existing line of preclinical, high sensitivity bioluminescence andfluorescence molecular optical imaging offerings. This additional capabilitywill further advance cardiovascular, neurology, immunology and oncologydistribution studies conducted using in vivo imaging.
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With the launch of the IVIS Kinetic system, researchers are now able tovisualize, track, quantify and understand biological processes in real time-asthe action happens-driving visual exploration and analysis of gene expression,cellular pathways and drug response. The IVIS Kinetic system features anisolation chamber that allows users to monitor conscious mice freely walkingand performing tasks. By capturing images and live video, at the molecularlevel, researchers can witness dynamic processes and reactions, enhancing theunderstanding of a drug candidate's potential performance in clinical studies.Specifically, by allowing researchers to view the real-time distribution ofdrugs and an animal model's responses to a compound, a more thoroughunderstanding of a drug's potential can be assessed.
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"The IVIS Kinetic imaging system provides a window for scientists to viewbiological events as they happen," said Kevin Hrusovsky, president and chiefexecutive officer, Caliper Life Sciences. "This system is another greatexample of how Caliper Life Sciences is helping pharma and biotech companiesunderstand complex biological processes to accelerate the discovery ofsuccessful drug candidates."

Caliper's IVIS imaging systems have played a significant role indemonstrating the efficacy of various drugs, including Sutent(R) (Pfizer),Sprycel(R) (dasatinib) (Bristol-Myers Squibb), Tasigna(R) (Novartis), andCubicin(R) (Cubist Pharmaceuticals).

Caliper offers a broad portfolio of imaging systems. For additionalinformation or to order the IVIS Kinetic, please visit:http://www.caliperls.com/products/optical-imaging/.

About Caliper Life Sciences

Caliper Life Sciences is a premier provider of cutting-edge technologiesenabling researchers in the life sciences industry to create life-saving andenhancing medicines and diagnostic tests more quickly and efficiently. Caliperis aggressively innovating new technology to bridge the gap between in vitroassays and in vivo results and then translating those results into cures forhuman disease. Caliper's portfolio of offerings includes state-of-the-artmicrofluidics, lab automation & liquid handling, optical imaging technologies,and discovery & development outsourcing solutions. For more information pleasevisit http://www.caliperLS.com.

Caliper and IVIS are registered trademarks of Caliper Life Sciences, Inc.Sutent is a registered trademark of Pfizer, Inc. Sprycel(R) is a registeredtrademark of Bristol-Myers Squibb. Tasigna is a registered trademark ofNovartis. Cubicin is a registered trademark of Cubist Pharmaceuticals.

SOURCE Caliper Life Sciences, Inc.
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