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Burgeoning Population of Hepatitis C Virus Patients in Need of Second- and Third-Line Treatment Options

Wednesday, September 5, 2007 General News
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WALTHAM, Mass., Sept. 5 Decision Resources, one of theworld's leading research and advisory firms focusing on pharmaceutical andhealthcare issues, has found that a significant proportion of hepatitis Cvirus (HCV) patients do not achieve a sustained virologic response or are notable to tolerate current first-line treatment. According to the new reportentitled Hepatitis C Virus Patient Flow Model and Treatment Algorithm,although currently available therapies can cure HCV, these agents areeffective in only about half of all patients who receive therapy. The lack ofavailable efficacious second- and third-line therapies leads to theaccumulation of patients who are non-responsive to first-line therapy. BecauseHCV is not a highly fatal disease, this growing population is awaiting thelaunch of novel therapies and represents an important segment in the HCVmarket.
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Hepatitis C virus represents a large commercial opportunity for drugdevelopers due to its high prevalence, the relatively poor efficacy and sideeffects of current therapies and its large undiagnosed and under treatedpopulation.
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"A sizeable cohort of the HCV-infected patients is aging, developingprogressive liver disease, and is awaiting the introduction of severalinnovative new therapies in late-stage development," said John Lebbos, M.D.,therapeutic area director at Decision Resources. "However, over the longerterm, the size of the candidate population for treatment will be limited dueto the dramatic decreases in the incidence of HCV that have been achieved aswell as the improved efficacy of novel agents."

Based on this report, Decision Resources is offering an exclusive, in-depth webinar entitled Hepatitis C Virus: Forecasting the Drug-Treated andTreatment Eligible Populations from 2006 to 2021. The webinar, presented byDr. Lebbos, will be held at 10 AM (EDT) on September 25, 2007. To register,visit http://www.DecisionResources.com.

About Hepatitis C Virus Patient Flow Model and Treatment Algorithm

This specialized report includes a detailed, annualized patient forecastmodel of the HCV population from 2006 to 2021 which includes the incidence-and mortality-based model includes estimates of the number of patientseligible for first-, second-, third, and fourth-line treatment by genotype andthe impact of novel, more effective therapies on the epidemic and treatment-eligible populations. The HCV patient flow model also allows the user toadjust key assumptions, providing the model with flexibility to modeldifferent scenarios.

About Treatment Algorithm Insight Series

Decision Resources combines in-depth primary research with the mostextensive claims-based longitudinal patient-level data from PharMetrics(R) toprovide exceptional insight into physicians' prescribing trends and thefactors that drive therapy product choice, from diagnosis through multiplecourses of treatment, for a specific disease.

About Decision Resources

Decision Resources, Inc., (http://www.DecisionResources.com) is a worldleader in healthcare market research publications, advisory services, andconsulting designed to help clients shape strategy, allocate resources, andmaster their chosen markets.

All company, brand, or product names contained in this document may betrademarks or registered trademarks of their respective holders.For more information, contact: Elizabeth Marshall Decision Resources, Inc. 781-296-2563 [email protected]

SOURCE Decision Resources, Inc.
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