Asarina Pharma raises EURO 7 million to develop a treatment for a disabling form of premenstrual syndrome, commonly known as PMDD

Monday, November 7, 2016 Drug News J E 4

STOCKHOLM, Nov. 7, 2016 /PRNewswire/ -- Asarina Pharma, a drug development company focused on the development of a novel therapy for severe premenstrual symptoms, has completed a financing round raising EURO 7 million from new and existing investors for the continued clinical development of Sepranolone.

Around 5% of women in fertile age worldwide suffer from Premenstrual Dysphoric Disorder (PMDD), a debilitating condition that prevents sufferers from leading a normal working and social life. Despite the high prevalence of the disease and the severity of its symptoms, there is low awareness of PMDD, and the pharmaceutical industry has so far been unable to meet this medical need. PMDD is caused by altered brain sensitivity to an endogenous steroid produced after ovulation resulting in monthly recurrent episodes of depression, anxiety and mood lability. As of today, treatment options include anti-depressants and oral contraceptives, but they have shown little effect, and are generally poorly accepted by the patients.

Asarina's lead candidate, Sepranolone, could become a game changer. Sepranolone, the first potential therapy to target the underlying cause of this condition, has shown promising results in an exploratory clinical Phase I/II study. Using the funds from current, and new investors Idinvest Partner (France) and Ergomed plc, Asarina is now preparing a Phase IIb clinical trial, to be conducted in the US and a number of European countries, among them Sweden.

Peter Nordkild, CEO of Asarina Pharma, said: "We are delighted to have attracted new investments from Idinvest and Ergomed, as well as our current stakeholders. Long-term investors have played a central role in helping Asarina secure the financial resources needed to reach this next crucial milestone. The planned Phase IIb study is an important next step in the clinical development of Sepranolone.


About Asarina Pharma AB

Asarina Pharma AB is a Swedish biotech company focusing on the development of Sepranolone (UC1010) for the treatment of premenstrual dysphoric disorder and other menstrually related conditions. The company's primary goal is to offer a novel therapy that is specifically designed for PMDD. Asarina has a second generation oral compound in preclinical development for PMDD. For more information, please visit:

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SOURCE Asarina Pharma



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