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Archivel Farma's TB Vaccine May Cut Treatment Time From Nine Months to One

Wednesday, May 5, 2010 General News
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BIO CONVENTION, CHICAGO, Illinois, May 5, 2010 ArchivelFarma, S.L. has announced that its breakthrough treatment for tuberculosis(TB) will shortly start phase II clinical trials. The treatment uses thecompany's unique combination of its novel therapeutic vaccine called RUTI(R)in conjunction with an antibiotic. This cuts treatment time from nine monthsto one month, which reduces side effects and healthcare costs, by preventingre-infection during the eradication process. The company expects commercialavailability in 2015.
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It has now been discovered that TB does not lie "dormant" but is actuallywaging a constant war with the host, constantly re-infecting the lungs.Provided that the host is healthy, it has the upper hand and usually keepsthe TB in check - LTBI. TB is particularly tricky to eliminate as it can beeither replicating, when it can be killed by the antibiotics, ornon-replicating when antibiotics are useless. The long, nine month course ofantibiotics is needed to ensure that all traces of the non-replicating formare eliminated from the lungs. Further details can be found athttp://www.archivelfarma.com/hipotesi_an.html
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Archivel's novel, two pronged approach combines a one month course ofantibiotic to eliminate the bacteria in the replicating stage and twoinjections of the company's RUTI vaccine that stimulates the body's ownimmune system to fight the TB bacteria. This combination approach reduces thetreatment time from nine months to one, is easier to manage, less expensive,more effective and more likely to be done completely. The company estimatesthat cost comparison between the current and new treatment, when allowing forall the logistical costs means that the new treatment costs around half thatof the old treatment.

Further information at http://www.archivelfarma.com/noticies_an.html

Full details can be found in the accompanying press release AF004002entitled "Archivel's RUTI, a novel therapeutic vaccine to LatentTuberculosis, starts phase II clinical trials in South Africa" and pressrelease AF004001 entitled "Major breakthrough in fight to eliminateTuberculosis".

Further information on Archivel at http://www.archivelfarma.com

Archivel Farma S.L., 61 c/ Fogars de Tordera, Poligon IndustrialBonavista, 08916 BADALONA, Spain. Tel +34-93-497-2456, +34-637-057432,[email protected]

Press information and illustrations

Nigel Robson, Vortex PR, Tel +44(0)1481-233080, [email protected]

RUTI is a registered trademark of Archivel Farma S.L.

SOURCE Archivel Farma
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