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Apieron, Inc. Begins Customer Shipments of the Insight(TM) eNO System

Friday, May 2, 2008 General News
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MENLO PARK, Calif., May 1 Apieron, Inc.(http://www.apieron.com) announced today that it has begun shipments of itsInsight(TM) eNO System. Cleared by the FDA in March 2008, the Insight eNOSystem combines the accuracy, speed, and ease-of-use needed for the healthcareprofessional to provide office-based measurements of exhaled nitric oxide(eNO). Exhaled nitric oxide is a well established clinical indicator ofairway inflammation and asthma control. With the use of eNO measurements,physicians can adjust inhaled corticosteroid therapy to optimize asthmacontrol and avoid exacerbations or 'asthma attacks'.
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The Insight eNO System's proprietary biosensor technology accuratelymeasures eNO in parts per billion. Its single-use breath tubes are designedto be hygienic and convenient for the patient, and the disposable sensorgenerates a reading in less than a minute. Patient data can be stored andmaintained in a unique format for trend analysis and printed for insurers' andpatients' files. All of the System's functions are accessible through a smalldesktop monitor with a large color display and clinician-friendly interface.
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"We showcased the Insight System at the March meeting of the AmericanAcademy of Allergy, Asthma and Immunology, and physicians respondedenthusiastically to its graphical interface and its elegant technology," saidRich Lotti, President and CEO of Apieron, Inc. "As current methods formonitoring asthma airway inflammation are subjective, the Insight eNO Systemprovides quantifiable information to increase therapeutic compliance. Webelieve this product will enable physicians to optimize medical therapy on anindividualized basis, and therefore improve the standard of care for patientswith asthma."

Sales and distribution of the Insight eNO System have been initiated withthe introduction of an Apieron National Direct Sales Force in targeted majormetropolitan regions.

About Apieron Inc.

Apieron Inc. is a private, venture-backed medical device company based inMenlo Park, CA that was funded in 2003 to develop a simple-to-use, non-invasive monitor for the measurement of exhaled nitric oxide (eNO) for themanagement of asthma. The Apieron biosensor technology platform utilizes apatented technology that allows for the highly sensitive detection of selectedanalytes such as eNO. Apieron is committed to collaborating with physiciansand patients to develop innovative medical solutions to improve quality oflife and standards of care.Refer Questions to: Holly McGarraugh Apieron, Inc. 650-454-8101

SOURCE Apieron, Inc.
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