PHARMA - Ranitidine

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Ranitidine

Ranitidine - Aciloc, Histac,Nilcer, R-Loc, Ranitidine-AD, Ranitin, , Rantac, Renitab, Ulcitab, Ultidin, Zinetac, Zonran
Use:

Short-term treatment of active duodenal ulcers and benign gastric ulcers; long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, gastroesophageal reflux, recurrent postoperative ulcer, upper GI bleeding, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine

Pregnancy & Lactation :
Risk Factor - B
Warnings & Precautions:

Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency

Contraindication:

Hypersensitivity to ranitidine or any component

Adverse Reactions :

Endocrine & metabolic: Gynecomastia; Hepatic: Hepatitis; Neuromuscular & skeletal: Arthralgia
1% to 10% : Central nervous system: Dizziness, sedation, malaise, headache, drowsiness; Dermatologic: Rash; Gastrointestinal: Constipation, nausea, vomiting, diarrhea;
<1% : Bradycardia, tachycardia, fever, confusion, thrombocytopenia, neutropenia, agranulocytosis, bronchospasm


Interactions :

Decreased effect: Variable effects on warfarin; antacids may decrease absorption of ranitidine; ketoconazole and itraconazole absorptions are decreased; may produce altered serum levels of procainamide and

ferrous sulfate; decreased effect of nondepolarizing muscle relaxants, cefpodoxime, cyanocobalamin (decreased absorption), diazepam, oxaprozin Decreased toxicity of atropine Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glipizide, glyburide, midazolam (increased concentrations), metoprolol, pentoxifylline, phenytoin, quinidine

Over Dose / Poisoning :

Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression Treatment is primarily symptomatic and supportive


Dosage :

Giving oral dose at 6 PM may be better than 10 PM bedtime, the highest acid production usually starts at approximately 7 PM, thus giving at 6 PM controls acid secretion better
children: Oral: 1.25-2.5 mg/kg/dose every 12 hours; maximum: 300 mg/day I.M., I.V.: 0.75-1.5 mg/kg/dose every 6-8 hours, maximum daily dose: 400 mg Continuous infusion: 0.1-0.25 mg/kg/hour (preferred for stress ulcer

prophylaxis in patients with concurrent maintenance I.V.s or TPNs) Adults: Short-term treatment of ulceration: 150 mg/dose twice daily or 300 mg at bedtime Prophylaxis of recurrent duodenal ulcer: Oral: 150 mg at bedtime Gastric hypersecretory conditions: Oral: 150 mg twice daily, up to 600mg/day I.M., I.V.: 50 mg/dose every 6-8 hours (dose not to exceed 400 mg/day) I.V.: 50 mg/dose IVPB every 6-8 hours (dose not to exceed 400 mg/day) or Continuous I.V. infusion: Initial: 50 mg IVPB, followed by 6.25 mg/hour titrated to gastric pH >4.0 for prophylaxis or >7.0 for treatment; continuous I.V. infusion is preferred in patients with active bleeding Gastric hypersecretory conditions: Doses up to 2.5 mg/kg/hour (220 mg/hour) have been used Dosing adjustment in renal impairment: Clcr 10-50 mL/minute: Administer at 75% of normal dose or administer every 18-24 hours Clcr <10 mL/minute: Administer at 50% of normal dose or administer every 18-24 hours Hemodialysis: Slightly dialyzable (5% to 20%) Dosing adjustment/comments in hepatic disease: Unchanged ADMINISTRATION Ranitidine injection may be administered I.M. or I.V., I.M.: Injection is given undiluted I.V. must be diluted and may be administered IVP or IVPB or continuous I.V. infusion. IVP: Ranitidine (usually 50 mg) should be diluted to a total of 20 mL with NS or D5W and administered over at least 5 minutes. IVPB: administer over 15-20 minutes. Continuous I.V. infusion: Administer at 6.25 mg/hour and titrate dosage based on gastric pH by continuous infusion over 24 hours


Patient Information :

It may take several days before this medicine begins to relieve stomach pain; antacids may be taken with ranitidine unless your physician has told you not to use them; wait 30-60 minutes between taking the antacid and ranitidine; may cause drowsiness, impair judgment, or coordination

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0098525 

IM LIVING IN PHILIPPINES. IN METRO MANILA.HOW CAN I BUY THE AN Amitriptyline HERE.? BUT I CANT BUY IT ONLINE
PLS MESSAGE ME IN MY YAHOO IF ANYONE CAN HELP ME
[email protected]

ricci 

can ferrous sulfate overdose be a cause of memory loss or memory degeneration? i know a friend who overdosed himself with more than 50 capsules of United Home ferrous sulfate in a suicidal attempt. Luckily, he's still alive. he storied to me that after few hours of overdosing FeSO4, he vomited and his stool became very dark brown. After that, his life became normal although he's complaining that most of the times, he suddenly forgets facts/information which he already memorized or been too long to know such info. There are also times that when he's too much drunk, he can't remember any detail or any information of things that have transpired when he became drunk. i hope you can help me.

ASHISHMARBADE 

I HAVE KNOW VERY GOOD INFORMATION FROM YOUR WEB PORTAL. ASHISH

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