PHARMA - Oxybutynin

Email Comment bookmark
Font : A-A+

Oxybutynin

Oxybutynin - Oxyspas, Tropan
Use:

Antispasmodic for neurogenic bladder (urgency, frequency, urge incontinence) and uninhibited bladder.

Pregnancy & Lactation :
Risk Factor - B
Warnings & Precautions:

Use with caution in patients with urinary tract obstruction, angle-closure glaucoma, hyperthyroidism, reflux esophagitis, heart disease, hepatic or renal disease, prostatic hypertrophy, autonomic neuropathy, ulcerative colitis (may cause ileus and toxic megacolon), hypertension, hiatal hernia. Caution should be used in elderly due to anticholinergic activity (eg, confusion, constipation, blurred vision, and tachycardia).

Contraindication:

Glaucoma, myasthenia gravis, partial or complete GI obstruction, GU obstruction, ulcerative colitis, hypersensitivity to drug or specific component, intestinal atony, megacolon, toxic megacolon

Adverse Reactions :

>10%: Central nervous system: Drowsiness Gastrointestinal: Xerostomia, constipation Miscellaneous: Diaphoresis (decreased) 1% to 10%: Cardiovascular:

Tachycardia, palpitations Central nervous system: Dizziness, insomnia, fever, headache Dermatologic: Rash Endocrine & metabolic: Decreased flow of breast milk, decreased sexual ability, hot flashes Gastrointestinal: Nausea, vomiting Genitourinary: Urinary hesitancy or retention Neuromuscular & skeletal: Weakness Ocular: Blurred vision, mydriatic effect <1%: Increased intraocular pressure, allergic reaction
Interactions :

Increased toxicity: Additive sedation with CNS depressants and alcohol Additive anticholinergic effects with antihistamines and anticholinergic agents

Over Dose / Poisoning :

Over Dose / Poisoning : Symptoms of overdose include hypotension, circulatory failure, psychotic behavior, flushing, respiratory failure, paralysis, tremor, irritability, seizures, delirium, hallucinations, coma

Symptomatic and supportive treatment; induce emesis or perform gastric lavage followed by charcoal and a cathartic; physostigmine may be required; treat hyperpyrexia with cooling techniques (ice bags, cold applications, alcohol sponges)

Dosage :

Children: 1-5 years: 0.2 mg/kg/dose 2-4 times/day >5 years: 5 mg twice daily, up to 5 mg 4 times/day maximum
Adults: 5 mg 2-3 times/day up to 5 mg 4 times/day maximum
Extended release: Initial: 5 mg once daily, may increase in 5-10 mg increments; maximum: 30 mg daily Elderly: 2.5-5 mg twice daily; increase by 2.5 mg increments every 1-2 days

Patient Information :

Take prescribed dose preferably on an empty stomach (1 hour before or 2 hours after meals). You may experience dizziness, lightheadedness, or drowsiness (use caution when driving or engaging in tasks requiring

alertness until response to drug is known); dry mouth or changes in appetite (small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may help);constipation (frequent exercise or increased dietary fiber, fruit, and fluid or stool softener may help); decreased sexual ability (reversible with discontinuance of drug); decreased sweating (use caution in hot weather, avoid extreme exercise or activity). Report rapid heartbeat, palpitations, or chest pain; difficulty voiding; or vision changes. Swallow extended-release tablets whole, do not chew or crush. Breast-feeding precautions: Do not breast-feed.

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
0098525 

IM LIVING IN PHILIPPINES. IN METRO MANILA.HOW CAN I BUY THE AN Amitriptyline HERE.? BUT I CANT BUY IT ONLINE
PLS MESSAGE ME IN MY YAHOO IF ANYONE CAN HELP ME
[email protected]

ricci 

can ferrous sulfate overdose be a cause of memory loss or memory degeneration? i know a friend who overdosed himself with more than 50 capsules of United Home ferrous sulfate in a suicidal attempt. Luckily, he's still alive. he storied to me that after few hours of overdosing FeSO4, he vomited and his stool became very dark brown. After that, his life became normal although he's complaining that most of the times, he suddenly forgets facts/information which he already memorized or been too long to know such info. There are also times that when he's too much drunk, he can't remember any detail or any information of things that have transpired when he became drunk. i hope you can help me.

ASHISHMARBADE 

I HAVE KNOW VERY GOOD INFORMATION FROM YOUR WEB PORTAL. ASHISH

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

CME Lessons