Ferrous Sulphate

Use:
Prevention and treatment of iron deficiency anemias

Pregnancy & Lactation :
Risk Factor - A
Warnings & Precautions:

Administration of iron for >6 months should be avoided except in patients with continued bleeding, menorrhagia, or repeated pregnancies; avoid in patients with peptic ulcer, enteritis, or ulcerative colitis. Anemia in the elderly is often caused by "anemia of chronic disease" or associated with inflammation rather than blood

loss. Iron stores are usually normal or increased, with a serum ferritin >50 ng/mL and a decreased total iron binding capacity. Hence, the "anemia of chronic disease" is not secondary to iron deficiency but the inability of the reticuloendothelial system to reclaim available iron stores.

Contraindication:
Hemochromatosis, hemolytic anemia; known hypersensitivity to iron salts
Adverse Reactions :

>10 %: Gastrointestinal: GI irritation, epigastric pain, nausea, dark stool, vomiting, stomach cramping, constipation .
1% to 10 %: Gastrointestinal: Heartburn, diarrhea Genitourinary:Discoloration of urine Miscellaneous: Liquid preparations may temporarily stain the teeth.
<1 %: Contact irritation

Interactions :

Decreased effect: Absorption of oral preparation of iron and tetracyclines are decreased when both of these drugs are given together;

concurrent administration of antacids may decrease iron absorption;iron may decrease absorption of penicillamine when given at the same time;response to iron therapy may be delayed in patients receiving chloramphenicol; milk may decrease absorption of iron. Increased effect: Concurrent administration > or =200 mg vitamin C per 30 mg elemental Fe increases absorption of oral iron.


Over Dose / Poisoning :

Symptoms of overdose include acute GI irritation; erosion of GI mucosa, hepatic and renal impairment, coma, hematemesis, lethargy, acidosis.Following treatment for fluid losses, metabolic acidosis, and shock, a severe iron overdose may be treated with deferoxamine.Deferoxamine may be administered I.V. (80 mg/kg over 24 hours) or I.M. (40-90 mg/kg every 8 hours). Usual toxic dose of elemental iron: > or = 35 mg/kg.


Dosage :

Oral: Children (dose expressed in terms of elemental iron): Severe iron deficiency anemia: 4-6 mg Fe/kg/day in 3 divided doses Mild to moderate iron deficiency anemia: 3 mg Fe/kg/day in 1-2 divided doses Prophylaxis:1-2 mg Fe/kg/day up to a maximum of 15 mg/day Adults (dose expressed in terms of ferrous sulfate):Iron deficiency: 300 mg twice daily up to 300 mg 4 times/day or 250 mg (extended release) 1-2 times/day Prophylaxis: 300 mg/day .


Patient Information :

May color stool black, take between meals for maximum absorption; may take with food if GI upset occurs, do not take with milk or antacids; keep out of reach of children.





Comments

0098525, Philippines

IM LIVING IN PHILIPPINES. IN METRO MANILA.HOW CAN I BUY THE AN Amitriptyline HERE.? BUT I CANT BUY IT ONLINE
PLS MESSAGE ME IN MY YAHOO IF ANYONE CAN HELP ME
[email protected]

ricci, Philippines

can ferrous sulfate overdose be a cause of memory loss or memory degeneration? i know a friend who overdosed himself with more than 50 capsules of United Home ferrous sulfate in a suicidal attempt. Luckily, he's still alive. he storied to me that after few hours of overdosing FeSO4, he vomited and his stool became very dark brown. After that, his life became normal although he's complaining that most of the times, he suddenly forgets facts/information which he already memorized or been too long to know such info. There are also times that when he's too much drunk, he can't remember any detail or any information of things that have transpired when he became drunk. i hope you can help me.

ASHISHMARBADE, India

I HAVE KNOW VERY GOOD INFORMATION FROM YOUR WEB PORTAL. ASHISH