Risk factors for coronary heart disease - Atherosclerosis is responsible for almost all cases of CHD. This insidious process begins with fatty streaks which are first seen in adolescence; these lesions progress into plaques in early adulthood, and culminate in thrombotic occlusions and coronary events in middle age and later life.
A variety of factors, often acting in concert, are associated with an increased risk for atherosclerotic plaques in coronary arteries and other arterial beds. Risk factor assessment is useful in adults to guide therapy for dyslipidemia, hypertension, and diabetes. A 12 year follow-up of 14,786Finnish men and women,
Differences in serum total cholesterol, blood pressure, body mass index, and prevalence of diabetes accounted for about one-third of the age-related increase in CHD prevalence in men and 50 to 60 percent in women.
Cardiovascular risk factors promote coronary disease in either sex at all ages but with different strengths.
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