Malaria has a propensity for grading peimips and highly prevalent during 2nd trimester. Congenital malaria due to vertical transmission from mother predisposes to low birth weight IUGR and abortion. Other significant implications are Anemia, Hypoglycemia lung injury and ARDS.
Proquanil is probably is the only safe drug during pregnancy. However, Chloroquine, Quinine are safe to use. Other antimalarial drugs are not recommended for use in pregnancy unless the benefits overweigh the risks.
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