The myeloproliferative disorders include chronic myelogenous leukemia, polycythemia vera, myelofibrosis and essential thrombo-cythemia (Table 7). Because all of these entities may present with leukocytosis, differentiation can be difficult and usually requires special laboratory studies and bone marrow examinations.
|Table 7 - Characteristic Features of Myeloproliferative Diseases|
|Disease cells||Red blood cells||White blood||Platelets||Marrow|
|Polycythemia vera||Increased||Normal or increased||Normal or increased||Hypercellular|
|Chronic myelogenous leukemia||Normal or increased||Increased||Normal or increased||Hypercellular|
|Myelofibrosis||Normal or||Variable decreased||Variable||Fibrosis|
|Essential thrombocythemia||Normal or decreased||Slightly increased or normal||Increased||Hypercellular|
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