Diagnosis and Management of Alcohol Problems

Email Comment bookmark
Font : A-A+

Medications

A variety of effective medications for treating alcoholism will likely become available in the near future.


This Food and Drug Administration has approved naltrexone for the treatment of alcoholism. Naltrexone was the first medication in 40 years (since disulfiram) to be approved specifically for this purpose.

Naltrexone is safe and effective in doses of 50 mg/day for alcoholics without liver disease. In very high doses (300 mg/day) naltrexone causes elevations of liver enzymes. Such doses, therefore, are not used to treat alcoholics. Furthermore, naltrexone has not been studied in patients with alcoholic liver disease, so its safety in such patients is unknown.

Because of the idiosyncratic, potentially fatal, drug-induced hepatitis that can occur with the use of disulfiram, it is not recommended for patients with liver disease.

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
schemer 

I'm confused, other websites said that oral contraceptives can decrease GGT levels. But here you say the opposite. What's the truth?

CME Lessons

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor