Review the side-effects of Penicillamine as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Central Nervous System- Peripheral sensory and motor nerve disease (including Guillain-Barré syndrome), psychic disturbances, mental disorders, agitation, anxiety.
Skin- Hives, scaly inflammation of the skin, hair loss, mucocutaneous disease, detachment of the top layer of skin from the lower layers of the skin, increased skin friability, excessive wrinkling, development of small white papules at venipuncture(IV therapy) and surgical sites, yellow nail syndrome.
Eye and ENT- Perception of sound within the human ear in the absence of corresponding external sound, inflammation of optic nerve, visual disturbances.
Gastrointestinal- Loss of appetite, abdomen pain, nausea, vomiting, diarrhea, diminished taste perception, peptic ulcers, inflammation of pancreas, oral ulcers.
Hormone- Inflammation of thyroid gland.
Blood- Decrease in white blood cells, platelets, and red blood cells, increase in number of monocytes in blood.
Liver- Drug induced liver disease.
Musculoskeletal- Joint pains, chronic autoimmune neuromuscular disease, involuntary movements.
Kidney- Protein in urine, blood in urine, kidney disorder, kidney failure.
Respiratory- Allergic Inflammation of the alveoli, irreversible lung disease, progressive scarring of both lungs, bronchial asthma.
Miscellaneous- Allergy, including generalized itching with early and late rashes, blistering; drug eruptions, autoimmune disease, vein inflammation, elevated body temperature, muscle inflammation, connective-tissue disease, increased size of breast, abnormal elastic tissue fibers, inflammatory destruction of blood vessels.
Cuprimine, Depen
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Central Nervous System- Peripheral sensory and motor nerve disease (including Guillain-Barré syndrome), psychic disturbances, mental disorders, agitation, anxiety.
Skin- Hives, scaly inflammation of the skin, hair loss, mucocutaneous disease, detachment of the top layer of skin from the lower layers of the skin, increased skin friability, excessive wrinkling, development of small white papules at venipuncture(IV therapy) and surgical sites, yellow nail syndrome.
Eye and ENT- Perception of sound within the human ear in the absence of corresponding external sound, inflammation of optic nerve, visual disturbances.
Gastrointestinal- Loss of appetite, abdomen pain, nausea, vomiting, diarrhea, diminished taste perception, peptic ulcers, inflammation of pancreas, oral ulcers.
Hormone- Inflammation of thyroid gland.
Blood- Decrease in white blood cells, platelets, and red blood cells, increase in number of monocytes in blood.
Liver- Drug induced liver disease.
Musculoskeletal- Joint pains, chronic autoimmune neuromuscular disease, involuntary movements.
Kidney- Protein in urine, blood in urine, kidney disorder, kidney failure.
Respiratory- Allergic Inflammation of the alveoli, irreversible lung disease, progressive scarring of both lungs, bronchial asthma.
Miscellaneous- Allergy, including generalized itching with early and late rashes, blistering; drug eruptions, autoimmune disease, vein inflammation, elevated body temperature, muscle inflammation, connective-tissue disease, increased size of breast, abnormal elastic tissue fibers, inflammatory destruction of blood vessels.
Other Precautions :
Penicillamine serum levels may be decreased if taken with food, take 1 hour before meals and at bedtime.Drug Name : Penicillamine
Penicillamine(Cuprimine) generic is a chelating agent (remove heavy metals from the body), prescribed for Wilson disease (excess copper in the body), severe rheumatoid arthritis that has not responded to other treatments, and cystinuria (excess amino acids in the urine, which causes kidney stones).Trade Names for Penicillamine
India :
International :
Cuprimine, Depen
