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Side effect(s) of Leflunomide


Review the side-effects of Leflunomide as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Body as a Whole
- Pus, cyst, fever, hernia, uneasiness, neck pain and pelvic pain.

  Heart
- Chest pain, headache, palpitation, fast heart rate and dilatation/inflammation of blood vessels.

  Gastrointestinal
- Gallstone, constipation, flatulence, inflammation of gastrointestinal tract, blood in stool, mouth infection, salivary gland enlargement and tooth disorder.

  Blood
- Anemia and skin discoloration.

  Metabolic
- Increased sugar/cholesterol/liver enzymes and swelling in the extremities.

  Musculoskeletal
- Joint/muscle pain, gangrene, bone pain, joint inflammation, muscle cramps and tendon rupture.

  Central Nervous System
- Anxiety, depression, dry mouth, sleeplessness, nerve pain, increased sweating and fainting.

  Respiratory
- Asthma, difficulty in breathing, nose bleed and lung disorder.

  Skin
- Pimples, inflammation, hair discoloration, blood clot, infection, rash, nail disorders, skin discoloration, skin nodule, subcutaneous nodule, skin ulcer and worsening psoriasis.

  Eye and ENT
- Blurred vision, cataract, inflammation of conjunctiva, eye disorder and taste perversion.

  Genitourinary
- Inflammation of bladder, painful urination, blood in urine, menstrual disorder, prostate disorder, urinary frequency and vaginal infection.

Other Precautions :

Patient may develop with serious liver or lung problem, monitor liver or lung function, complete blood counts during the treatment.

Drug Name : Leflunomide

Leflunomide(Arava tab) generic is a pyrimidine synthesis inhibitor, prescribed for rheumatoid arthritis. The medication reduces joint damage and enhances physical activity. It blocks certain enzymes responsible for abnormal tissue development or growth.


Trade Names for Leflunomide

India :


International :


Arava tab
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