Medindia LOGIN REGISTER
Medindia

Side effect(s) of Duloxetine


Review the side-effects of Duloxetine as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Heart
- Hot flushes, palpitations,abnormal heart rhythm,increased blood pressure,orthostatic hypotension.

  Central Nervous System
- Drowsiness, headache, dizziness,fatigue,agitation, tremor,abnormal dreams, suicidal thoughts, anxiety, sleep disorder, yawning, lethargy,aggression, anger, restless leg syndrome, activation of mania and hypomania when used for depression and seizures.

  Skin
- Abnormally increased sweating, allergic reactions with rash, itching, blistering, redness and edema of the skin.

  Eye and ENT
- Blurred vision, sudden increase in eye pressure, vertigo

  Serotonin Syndrome:
Symptoms include increased heart rate, tremors, sweating, seizures, nausea, vomiting and diarrhea.

  Gastrointestinal
- Nausea, dry mouth, constipation, vomiting, stomach pain,decreased appetite

  Liver:
Liver damage, liver failure

  Genitourinary
- Sexual dysfunction which may include impotence and delayed ejaculation, frequent urination, urinary hesitation and abnormal uterine bleeding in female patients.

  Musculoskeletal
- Muscle spasms

  Miscellaneous
- Chills/rigors, low blood sodium levels, abnormal bleeding.

Other Precautions :

Do not discontinue or stop the sudden use of duloxetine suddenly as it will cause withdrawal symptoms like dizziness, headache, irritability, vomiting and seizures.
Consult your doctor for dosage changes.
Consult your doctor if you are going to have any surgery while using duloxetine.
Check blood pressure regularly while taking duloxetine as the drug is capable of producing hypertension.

Drug Name : Duloxetine

Duloxetine(Cymbalta) generic Duloxetine belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors. It is prescribed for depression, generalized anxiety disorder and for managing chronic musculoskeletal pain caused by fibromyalgia and other conditions. It is used to treat diabetic peripheral neuropathy (damage to the nerves due to diabetes). Duloxetine acts by increasing the levels of both serotonin and norepinephrine neurotransmitters in the brain, which maintains the mental balance and stops the transmission of pain signals in the brain.


Trade Names for Duloxetine

India :


International :


Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela
Advertisement
Recommended Reading