How to Take Linagliptin and Metformin Hydrochloride and Dose of Linagliptin and Metformin Hydrochloride


Find out how to take Linagliptin and Metformin Hydrochloride (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Linagliptin and Metformin Hydrochloride


How it should be taken  

It comes as a tablet to take by mouth, with meals as directed by your doctor.

Dosage & When it is to be taken

Dose is based on patientís condition. The recommended dose is 2.5 mg linagliptin/1000 mg metformin hydrochloride twice daily.

When it is not to be taken (Contraindications) 

Contraindicated in patients with type 1 diabetes, stroke, recent heart attack, shock, severe infection, low blood oxygen levels, kidney or liver problems, and hypersensitivity.

Why it is prescribed (Indications)  

This combination medication contains dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide, prescribed for type 2 diabetes in certain patients along with diet and exercise.  

Pregnancy Category

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Warnings and Precautions  

Caution should be exercised in patients with history of heart disease, lung or breathing problems, thyroid problems, stomach problems, adrenal or pituitary problems, lactic acidosis, inflammation of the pancreas, gallstones, high blood cholesterol, alcohol abuse, angioedema, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
Avoid alcohol consumption.
Monitor kidney function, fasting blood glucose, hemoglobin A1c, and complete blood cell counts regularly while taking this medication.

Storage Conditions  

Store it at room temperature.
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