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How to Take Doxylamine Succinate and Pyridoxine Hydrochloride and it's Dose


It comes as a tablet to take by mouth on an empty stomach.

Dosage & When it is to be taken

Initially, take two DICLEGIS delayed-release tablets orally at bedtime (Day 1). If this dose adequately controls symptoms the next day, continue taking two tablets daily at bedtime. However, if symptoms persist into the afternoon of Day 2, take the usual dose of two tablets at bedtime that night then take three tablets starting on Day 3 (one tablet in the morning and two tablets at bedtime). If these three tablets adequately control symptoms on Day 4, continue taking three tablets daily. Otherwise take four tablets starting on Day 4 (one tablet in the morning, one tablet mid-afternoon and two tablets at bedtime).
The maximum recommended dose is four tablets (one in the morning, one in the mid-afternoon and two at bedtime) daily.

When it is not to be taken (Contraindications)

Contraindicated in patients with known hypersensitivity, asthma, increased intraocular pressure, narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, urinary bladder-neck obstruction and women who are taking monoamine oxidase inhibitors (MAOIs).

Drug Name : Doxylamine Succinate and Pyridoxine Hydrochloride

This combination medication is used to treat nausea and vomiting or morning sickness in pregnant women who do not respond to conservative management.


Trade Names/Brand Names of Doxylamine Succinate and Pyridoxine Hydrochloride

International :


Diclegis, Debendox, Lenotan, Merbental, Diclectin
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