How to Take Asenapine and Dose of Asenapine


Find out how to take Asenapine (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Asenapine


How it should be taken  

It comes as a tablet to be placed under the tongue, with or without food.

Dosage & When it is to be taken

Sublingual- The recommended starting and target dose is 5 mg given twice daily.

When it is not to be taken (Contraindications) 

Contraindicated in patients with severe liver problems, heart diseases, who are taking antiarrhythmic, antipsychotic, phenothiazine, quinolone drugs and hypersensitivity.

Why it is prescribed (Indications)  

This medication is an atypical antipsychotic agent, prescribed for schizophrenia and acute mania with bipolar disorder. It changes the activity of certain natural substances in the brain.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution should be exercised in patients with history of high blood pressure, cancer, Alzheimer disease, dementia, Parkinson disease, or esophagus problems, low blood volume, alcoholism, heart, liver, and kidney diseases, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause drowsiness, dizziness, or lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid alcohol consumption.
Avoid abrupt withdrawal; withdraw gradually.
Monitor complete blood cell counts, electrolyte levels, or fasting blood sugar levels regularly while taking this medication.
Patient may develop with increased risk of neuroleptic malignant syndrome (NMS) with the following symptoms: fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. If it is so consult with your doctor.
Avoid contact with people who have infections.
Drink adequate fluid; otherwise it may lead to dehydration.

Storage Conditions  

Store it at room temperature (25C).

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