How to Take Artemether and Lumefantrine and Dose of Artemether and Lumefantrine


Find out how to take Artemether and Lumefantrine (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Artemether and Lumefantrine


How it should be taken  

It comes as a tablet and capsule to take by mouth, with food.

Dosage & When it is to be taken

Adult: PO- A 3-day treatment schedule with a total of 6 doses is recommended for adult patients with a bodyweight of 35 kg and above: Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice daily (morning and evening) for the following two days (total course of 24 tablets). patients weighing less than 35 kg, should follow pediatric dosage.
Pediatric: Po- A 3-day treatment schedule with a total of 6 doses is recommended: 5 kg to less than 15 kg bodyweight: One tablet as an initial dose, 1 tablet again after 8 hours and then 1 tablet twice daily (morning and evening) for the following two days (total course of 6 tablets).
15 kg to less than 25 kg bodyweight: Two tablets as an initial dose, 2 tablets again after 8 hours and then 2 tablets twice daily (morning and evening) for the following two days (total course of 12 tablets).
25 kg to less than 35 kg bodyweight: Three tablets as an initial dose, 3 tablets again after 8 hours and then 3 tablets twice daily (morning and evening) for the following two days (total course of 18 tablets).
35 kg bodyweight and above: Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice daily (morning and evening) for the following two days (total course of 24 tablets).

When it is not to be taken (Contraindications) 

It should not be co-administered with CYP3A4 inducers and patients with known hypersensitivity.

Why it is prescribed (Indications)  

This medication is an antimalarial agent, prescribed for malaria. 

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution needed for patients with history of heart, liver or kidney disease, mental illness, electrolyte imbalance, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Avoid concomitant use of drugs known to prolong QT interval.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Do not eat grapefruit or drink grapefruit juice while taking this medication.

Storage Conditions  

Store it at room temperature (25C).

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Please note for the minimum order for Exports is of US$ 200. All orders will be subject to courier charges and supplies are normally dispatched through internationally accredited courier services.
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