How to Take Argatroban and Dose of Argatroban


Find out how to take Argatroban (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Argatroban


How it should be taken  

It comes as a solution for injection to be administered by a healthcare provider into the vein.

Dosage & When it is to be taken

IV- Initial Dosage: An infusion should be started at 25 mcg/kg/min and a bolus of 350 mcg/kg over 3 to 5 minutes. It may be adjusted if needed.

When it is not to be taken (Contraindications) 

Contraindicated in patients with severe bleeding, who are taking metronidazole, disulfiram, or heparin and hypersensitivity.

Why it is prescribed (Indications)  

This medication is an anticoagulant (thrombin inhibitor) agent prescribed for thrombosis treatment in patients with heparin-induced thrombocytopenia (low platelet levels).  

Pregnancy Category

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Warnings and Precautions  

Caution should be exercised in patients with history of heart disease, blood disorder, stroke, stomach or intestinal problem, low platelet counts (thrombocytopenia), high blood pressure, liver disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
It may cause bleeding or bruising, avoid injury.

Storage Conditions  

Store it at room temperature (25C), and in an airtight container.

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