How it should be taken
It comes as a tablet to take by mouth, with or without food.
Dosage & When it is to be taken
The maximum recommended dose is 40/10/25 mg. Available doses are 20 /5 /12.5 mg, 40 /5 /12.5 mg, 40 /5 /25 mg, 40 /10 /12.5 mg, 40 /10 /25 mg.
When it is not to be taken (Contraindications)
Why it is prescribed (Indications)
This combination medication contains amlodipine which is a channel blocker, Olmesartan an angiotensin II receptor blocker, and thiazide diuretic, prescribed for high blood pressure.
Category D :
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution should be exercised in patients with history of gallbladder, liver, or kidney problems; asthma, gout, lupus, low blood pressure, blood vessel problems, heart disease, high blood cholesterol, stroke, heart attack, low blood electrolyte levels, fluid retention, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, drowsiness, or blurred vision, do not drive a car or operate machinery while taking this medication.
It is not indicated for initial therapy.
Avoid alcohol consumption.
When taken too close to bedtime, patient might need to wake up to urinate. Therefore, it is best to take this medication at least 4 hours before bedtime.
Avoid exposure to sunlight.
Monitor blood pressure, sugar, kidney function, and blood electrolyte levels regularly while taking this medication.
♦Patient may develop increased risk due to Dual Blockade of the Renin-Angiotensin System (RAS).
It will cause birth defect or fetal and new born death if used during pregnancy. Therefore, it is important to prevent pregnancy while on this medication.
Tribenzor therapy should not be given with lithium due to the hydrochlorothiazide component, which causes reduced renal clearance of the lithium causing lithium toxicity.
Store at 25°C.