How to Take Aminocaproic Acid and Dose of Aminocaproic Acid


Find out how to take Aminocaproic Acid (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Aminocaproic Acid


How it should be taken  

It is available as a tablet, syrup and an injection.

Dosage & When it is to be taken

PO- Treatment and prophylaxis of haemorrhage- Initial: 4-5 g, then 1-1.25 g hourly, usually up to 8 hour or until bleeding has been controlled. Max: 30g/24 hour.
Patients with haemophilia undergoing dental extraction- Initial: 6 g immediately after extraction, then 6 g 6 hourly for up to 10 days.
IV- Treatment and prophylaxis of haemorrhage- As 2% solution: Initial: 4-5 g over 1 hour, then continuous infusion of 1 g/hour for usually up to 8 hour or until bleeding is controlled. Max: 24 g/24 hour

When it is not to be taken (Contraindications) 

Bleeding due to disseminated intravascular coagulation. Rapid IV administration.

Why it is prescribed (Indications)  

This medication is an antidote, prescribed for excessive bleeding caused by fibrinolytic drugs. It may also be used in some other conditions to stop excessive bleeding e.g.abruptio placentae, bleeding after delivery etc.  

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution should be exercised in patients with history of urinary tract bleeding, skeletal muscle disease, neonates, veno-occlusive hepatic disease (small veins in liver are blocked)or kidney disease.
Monitor creatinine phosphokinase level regularly.
Avoid administration with factor IX complex concentrates and during pregnancy and lactation.

Storage Conditions  

Injection: Store at 15-30�C. Store it in airtight container and keep away from children.

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