How it should be taken
It comes as a capsule to take by mouth, with food and at bedtime.
Dosage & When it is to be taken
Adult- PO- It may be administered either for 14 or 21 consecutive days in a 28 day cycle at a dose of 260 mg/m²/day.
When it is not to be taken (Contraindications)
Contraindicated in patients with preexisting severe bone marrow depression, and hypersensitivity.
Why it is prescribed (Indications)
This medication is an antineoplastic alkylating agent, prescribed for certain types of cancer such as ovarian cancer. It slows the cancer cells growth.
Category D :
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution should be exercised in patients with history of bone marrow cancer, bone marrow depression, decrease in white blood cells, liver problem, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may reduce platelet counts; avoid injury or bruising.
Store it at room temperature (25°C).