How to Take Aliskiren and hydrochlorothiazide and Dose of Aliskiren and hydrochlorothiazide


Find out how to take Aliskiren and hydrochlorothiazide (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Aliskiren and hydrochlorothiazide


How it should be taken  

It comes as a tablet to take by mouth, with or without food.

Dosage & When it is to be taken

Adult- Tablet- The recommended dose is 150/12.5 mg once daily, 150/25 mg or 300/12.5 mg, and 300/25 mg.

When it is not to be taken (Contraindications) 

Contraindicated in patients with anuria (absence of urination), severe kidney problems, and hypersensitivity.
Do not use aliskiren with angiotensin receptor blockers (ARBs) and the angiotensin converting enzyme inhibitors (ACEIs)in patients with diabetes.

Why it is prescribed (Indications)  

This medication is a direct renin inhibitor and thiazide diuretic combination, prescribed for high blood pressure.  It works by decreasing substances in the body that narrow blood vessels and raise blood pressure.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution should be exercised in patients with history of gout, lupus, sugar, asthma, heart, kidney, liver problems, kidney stones, thyroid problems, high blood cholesterol, receiving dialysis treatment, dehydration, who are in low-salt diet, blood electrolyte problems, severe allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness, lightheadedness, or fainting, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid alcohol consumption.
Patient may develop with serious side effect called angioedema with the following symptoms: swelling the hands, face, neck, etc; breathing trouble, and shock. If it is so consult with your doctor.
Avoid exposure to sunlight; otherwise it may cause sunburn.
It may affect sugar level; monitor blood sugar level regularly while taking this medication.
Monitor blood pressure, blood electrolyte levels, and kidney function regularly while taking this medication.

Storage Conditions  

Store it at room temperature (25C).
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