How it should be taken
It comes as a capsule to take by mouth, with food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein.
Dosage & When it is to be taken
Adult- PO- The recommended starting dose is 1mcg/day. Maintenance: 0.25-1 mcg/day.
Adult- IV- The recommended initial dose is 1 mcg per dialysis two to three times a week.
When it is not to be taken (Contraindications)
Contraindicated in patients with high blood calcium, phosphate, and magnesium and known hypersensitivity.
Why it is prescribed (Indications)
This medication is an analogue of vitamin D, prescribed for hypocalcaemia, hypoparathyroidism, hypophosphataemia, renal osteodystrophy, and osteomalacia. Since it does not require any activation process by kidneys like other vitamin D supplements, more useful for people who have kidney problems.
Category C :
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution should be exercised in patients with history of kidney stones, heart or kidney disease, high level of calcium in blood, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Monitor blood electrolytes level regularly while taking this medication.
Monitor serum levels of calcium in patients with kidney failure.
Capsules: Store it at room temperature (25°C), and in an airtight container.
Injection: Store it in a cool place (below 15°C).