How it should be taken
It comes as a tablet, should be taken on an empty stomach.
Dosage & When it is to be taken
PO: The recommended dose is 5 to 10mg once daily or 35 to 70mg tablet once weekly.
When it is not to be taken (Contraindications)
Contraindicated in patients with hypersensitivity, decreased level of calcium in blood, esophageal abnormalities and factors which delay esophageal emptying, severe kidney impairment, inability to stand or sit upright for more than half an hour, during pregnancy and breastfeeding.
Why it is prescribed (Indications)
This medication is a bisphosphonate, primarily used for prevention and treatment of osteoporosis in men and postmenopausal women. It is also used for Paget's disease and osteoporosis caused by steroid treatment. It reduces the amount of calcium released from the bones into the blood.
Category C :
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution needed in patients with history of upper gastrointestinal disorders (discontinue if symptoms worsen); ulcers and active gastrointestinal bleeding.
Correct vitamin D and calcium deficiency before starting therapy.
Not recommended for use in patients with CrCl <35 ml/min.
Proper dental care is important while taking this medication.
Do not drive a car or operate machinery, avoid alcohol and smoking while taking this medication.
Store it at room temperature and in an airtight container. Keep away from children and pets.