How it should be taken
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Dosage & When it is to be taken
Adult: IV- Acute hypovolemic shock- Initial: 25 g, adjust according to response. Usual rate: Up to 5 ml/min using 5% solution.
Hypoproteinaemia- Up to 2 g/kg/day. Usual rate: Up to 5 ml/min using 5% solution.
When it is not to be taken (Contraindications)
Contraindicated in patients with heart failure, severe anemia, history of hypersensitivity, parenteral nutrition (intravenous feeding of a person).
Why it is prescribed (Indications)
This medication is derived from human plasma, used to treat shock as a result of blood loss in the body (hypovolemia), burns, low protein levels (hypoproteinemia) due to surgery or liver failure, adult respiratory distress syndrome, dialysis, and as an additional medicine in bypass surgery. It increases blood plasma volume or serum albumin levels. It increases plasma volume or serum albumin levels.
Category C :
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution needed for patients with hypertension or low cardiac reserve, pulmonary edema and severe anemia.
Administration of additional fluids for dehydrated patients.
Monitor for signs of cardiac overload in injured or postoperative patients.
It may carry risk of viral transmission.
Blood volume administration and rate of infusion must always be individualized according to situation and response.
Caution should be exercised in patients with history of heart, kidney, and liver diseases.
Do not use sterile water for injection as a diluent, as this may cause haemolysis in recipients. It can also be diluted in an isotonic solution (e.g. 5% glucose or 0.9% sodium chloride).
Store below 30°C. Do not freeze. Store away from heat, moisture, and light.