How to Take Adefovir Dipivoxil and Dose of Adefovir Dipivoxil


Find out how to take Adefovir Dipivoxil (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Adefovir Dipivoxil


How it should be taken  

It comes as a tablet to take by mouth, with or without food.

Dosage & When it is to be taken

Adult- PO -The recommended dose is 10mg/day.

When it is not to be taken (Contraindications) 

Contraindicated in patients who are taking tenofovir, liver enlargement and hypersensitivity.

Why it is prescribed (Indications)  

This medication is a reverse transcriptase inhibitor (ntRTI), prescribed for hepatitis B, in patients 12 years of age and older with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease. and herpes simplex virus infection. It slows the growth of HBV by blocking reverse transcriptase, an enzyme that is helpful for viral reproduction.  It slows the growth of HBV by blocking reverse transcriptase, an enzyme that is helpful for viral reproduction.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution should be exercised in patients with history of kidney, liver diseases, abnormal liver function tests, liver transplant, HIV infection, obesity, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
It should not be used in children less than 12 years old.
Monitor kidney and liver functions regularly while taking this medication.
If condition worsens stop the medication immediately.
Should not be used concurrently with tenofovir disoproxil fumarate or tenofovir disoproxil fumarate-containing products.

Storage Conditions  

Store it in room temperature (25C), and in an airtight container.

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