How to Take Aclarubicin and Dose of Aclarubicin


Find out how to take Aclarubicin (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Aclarubicin


How it should be taken  

It comes as a solution for injection to be administered by a healthcare provider into the vein.

Dosage & When it is to be taken

Adult: IV- Initial: 175-300 mg/m2, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2 3-4 weekly.

When it is not to be taken (Contraindications) 

Contraindicated in patients with severe heart disease, bone marrow depression, and hypersensitivity.

Why it is prescribed (Indications)  

This medication is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. It has a selective inhibitory effect on the synthesis of RNA in the cells

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding.
Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication.

Storage Conditions  

IV Inj: Store at room temperature (20 to 25C). Protect from sunlight. IV Inj (reconstituted solution): Store below 40C. Use within 24 hours if kept at room temperature.

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