How it should be taken
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Dosage & When it is to be taken
Adult: IV- Initial: 175-300 mg/m2
, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2
When it is not to be taken (Contraindications)
Contraindicated in patients with severe heart disease, bone marrow depression, and hypersensitivity.
Why it is prescribed (Indications)
This medication is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. It has a selective inhibitory effect on the synthesis of RNA in the cells
Category D :
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding.
Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication.
IV Inj: Store at room temperature (20 to 25°C). Protect from sunlight.
IV Inj (reconstituted solution): Store below 40°C. Use within 24 hours if kept at room temperature.