How to Take Acitretin and Dose of Acitretin


Find out how to take Acitretin (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Acitretin


How it should be taken  

It comes as a capsule to take by mouth. It is usually taken once a day with the main meal.

Dosage & When it is to be taken

Adult: PO- The recommended dose is 25 to 50 mg per day, given as a single dose with the main meal.

When it is not to be taken (Contraindications) 

Contraindicated in patients with liver, kidney impairment, during pregnancy (before the start, during and at least 2-3 yr after cessation of therapy), lactation, increased level of lipids in blood.

Why it is prescribed (Indications)  

This medication is a synthetic retinoid, prescribed for severe psoriasis (abnormal growth of skin cells that causes red, thickened, or scaly skin)It regulates the growth of epidermal cells. 

Pregnancy Category

Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Warnings and Precautions  

It may cause drowsiness or vision changes. Do not drive a car or operate machinery while taking this medication.
Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of this medication.
Sexually active women of childbearing age who use Acitretin should also use at least 2 forms of birth control concurrently.
Avoid blood donation during therapy or at least 1-3 years after stopping therapy.
It may make your skin sensitive to light, so avoid sunlight.
Remove contact lenses while using this medication otherwise it will increase irritation.
Monitor liver function, plasma lipid and glucose levels (especially in diabetic patients) regularly.

Storage Conditions  

Store between 15 and 25C (59 and 77F) in an airtight container. Protect from light. Avoid exposure to high temperatures and humidity after the bottle is opened. Keep away from children.

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