How to Take Acetaminophen and Oxycodone and Dose of Acetaminophen and Oxycodone


Find out how to take Acetaminophen and Oxycodone (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Acetaminophen and Oxycodone


How it should be taken  

It comes as a tablet, capsule and solution to take by mouth, with or without food.

Dosage & When it is to be taken

The usual adult dosage is one tablet every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams. The available dosages are oxycodone/acetaminophen 2.5/325, 7.5/325, 7.5/500, 10/325 and 10 /650 mg.

When it is not to be taken (Contraindications) 

Contraindicated in patients with significant respiratory depression, intestinal obstruction and hypersensitivity.

Why it is prescribed (Indications)  

This combination medication is a narcotic analgesic, prescribed for moderate to severe pain. Acetaminophen increases the effects of Oxycodone, which is an opioid pain medication.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Warnings and Precautions  

Caution should be exercised in patients with history of liver or kidney diseases, heart problems, lung disease, seizure disorders, serious head injury or brain diseases, spinal problems, underactive thyroid, adrenal gland problems, breathing problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, lightheadedness, blurred vision or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid alcohol consumption.
It may lead to constipation; take proper diet, drink adequate water and avoid antidiarrheals while on this medication.

Storage Conditions  

Store it at room temperature (20 to 25C) and in an airtight light- resistant container. Keep away from children.

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