How it should be taken
It comes as a tablet to take by mouth, on an empty stomach.
Dosage & When it is to be taken
Adult- PO- The recommended dose is 1000mg once daily with prednisone 5mg twice daily.
When it is not to be taken (Contraindications)
Contraindicated in pregnant women and patients with hypersensitivity.
Why it is prescribed (Indications)
This medication is a chemotherapy agent, prescribed for prostate cancer in patients who have received prior chemotherapy containing docetaxel. It is used either alone or with other medications (prednisone).
Category X :
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Warnings and Precautions
Caution should be exercised in patients with history of heart disease, high blood pressure, decrease in blood potassium level, adrenal gland insufficiency, liver or kidney disease, elderly, and in children.
Monitor liver function, adrenocortical insufficiency, regularly while taking this medication.
Women who are pregnant or who may be pregnant should not handle ZYTIGA without protection, e.g., gloves.
Store it at room temperature (20° to 25°C), and in an airtight container.