How it should be taken
It is administered as an injection into the vein (intravenously), or as a solution for subcutaneous (under the skin) injection by a healthcare provider every 2 weeks for the first 3 doses and then every 4 weeks.
Dosage & When it is to be taken
Dose is based on body weight and condition of the patient. Weight < 60 kg should receive 500 mg dose, weight 60-100 kg a 750 mg dose and weight >100 kg a 1000 mg dose.
Juvenile Idiopathic Arthritis- Pediatric patients weighing less than 75 kg: receive 10 mg/kg.
When it is not to be taken (Contraindications)
Why it is prescribed (Indications)
This medication is a synthetic protein, prescribed for adult with moderate to severe rheumatoid arthritis including patients who have not responded to DMARDs (disease-modifying anti-rheumatic drugs), and juvenile idiopathic arthritis. It blocks the activity of T-cells, which causes swelling and joint damage in people with arthritis condition.
Category C :
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Warnings and Precautions
Patient may develop with serious infections and tumor. Caution should be exercised in patients with history of lung, nerve diseases (e.g. multiple sclerosis), cancer, Human Immunodeficiency Virus (HIV), tuberculosis (TB), severe combined immunodeficiency syndrome (SCID), cut or open sore, diabetes (especially if you are checking your blood sugar level at home), during pregnancy and breastfeeding.
Avoid vaccination while taking this medication.
Normally handled and stored by healthcare providers in refrigerator. Do not freeze and keep it away from light.