Warfarin - Drug Toxicity

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Latest prescription information about Warfarin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Drug Name : Warfarin

Indication : Warfarin is an oral anticoagulant.


Physiology : Warfarin is used for chronic oral anticoagulation in a variety of clinical symptoms. Management of warfarin therapy is usually done by following the prothrombin time.

Normal Values : 2-5 µg/mL (6.5-16.2 µmol/L)

Critical Values : >10 µg/mL (>32.4 µmol/L)


Test Method : High Performance Liquid Chromatography (HPLC), Gas Liquid Chromatography (GLC), UV-spectrophotometry.

Side effects : Side effects of warfarin include bleeding, osteoporosis or thinning of bones, gangrene of the skin, liver damage, and allergic reaction. Obstruction of the blood supply to the feet results in a condition called purple toe syndrome. It should not be administered during pregnancy due to possibility of congenital malformations, bleeding and abortion.

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