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 Medindia » Drug Toxicity » Carbamazepine
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Carbamazepine

Drug Name :  Carbamazepine


Indication :Carbamazepine is a first line antiepileptic drug for generalized and partial seizures. The drug is used to control pain in trigeminal neuralgia and in treatment of bipolar effective disorder.


Physiology :The addition of anticonvulsants which decrease carbamazepine level may cause seizures. Drugs which increases the concentration of carbamazepine causes delayed toxicity.


Normal Values :8-12 µg/ml (25-51 µmol/L)


Critical Values :Higher than normal values causes central nervous system toxicity


Test Method :Enzyme Immunoassay, Gas chromotography, HPLC


Side effects :Drug may cause increased toxicity


Related Drugs :Theophylline, Valporic acid, Warfarin.




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