Amphotericin B/ Fungizone - Drug Toxicity
Indication : Amphotericin B is a clinically useful but highly toxic antifungal agent. Monitor serum levels for potential toxicity and correlation with in vitro susceptibility testing.
Normal Values : Therapeutic: 1.0-2.0 mg/mL (1.0-2.0 mmol/L)
Side effects : Amphotericin B therapy frequently induces fever, chills, nausea, and reversible bone marrow suppression. The drug shows an acute deterioration in renal function, when Creatinine levels exceed 3.0 mg/mL.