Amitriptyline/ Etrafon, Triavil - Drug Toxicity

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Latest prescription information about Amitriptyline/ Etrafon, Triavil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Drug Name : Amitriptyline/ Etrafon, Triavil

Indication : Amitriptyline is a tricyclic anti-depressant and the test is done for therapeutic monitoring and toxicity assessment.


Physiology : Amitriptyline is a tricyclic antidepressant that blocks the reuptake of serotonin at nerve endings and possesses high anticholinergic activity and cardiovascular toxicity.

Normal Values : 100-250 ng/mL (360-900 nmol/L)

Critical Values :  > 300 g/mL (> 1080 nmol/L)


Test Method : Immunoassay, High Performance Liquid Chromatography (HPLC), Gas Chromatography (GC).

Side effects : Side effects include nausea, vomiting, dizziness, headache, drowsiness, restlessness, confusion, mood disturbances, anxiety, agitation, possible suicidal thoughts, blurred vision, dry mouth, urinary retention, increased appetite, weight gain, abnormal heart rhythms, low blood pressure and even seizures. Amitriptyline should be avoided in pregnant and lactating women because it has not been established as safe.

Related Drugs : Notriptyline, Tricyclic Antidepressants

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