Acetaminophen/ Paracetamol/ Liquiprin - Drug Toxicity

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Latest prescription information about Acetaminophen/ Paracetamol/ Liquiprin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Drug Name : Acetaminophen/ Paracetamol/ Liquiprin

Indication : Acetaminophen is an analgesic antipyretic widely used as a replacement of aspirin.


Physiology : Acetaminophen is an analgesic and an antipyretic with anti-inflammatory properties. It is used for the treatment of headache, fever, pain relief or inflammation. Acetaminophen is given, in place of aspirin, for the treatment of fever in children below the age of 14. This is due to the association of aspirin with the development of Reye’s syndrome.


Test Method : UV Spectrometry, High Performance Liquid Chromatography (HPLC), Immunoassay.

Interpretation : Hepatic toxicity may appear 3-5 days after ingestion of a toxic dose. Toxic levels require monitoring through liver function tests(AST, ALT, Bilirubin, Glucose, creatinine, prothrombin time and electrolytes).

Side effects : Possible side effects are dizziness, nausea, vomiting, lethargy, impaired mental and physical performance, and mood changes. Acute liver damage and hepatic failure occur due to paracetamol toxicity. Serious skin reactions like Steven Johnson Syndrome, Toxic Epidermal Necrolysis and acute generalized exanthematous pustulosis (AGEP) can even be fatal.

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