Melacare is a retinoid, prescribed for acne vulgaris and acute promyelocytic leukemia.  It slows or stops the growth of cancer cells in the body.

Drug information on Melacare (Tretinoin) from Ajanta Pharma Ltd.

Melacare

  Cream
Ajanta Pharma Ltd.
Generic : Tretinoin
 118.00
0.1%/0.025%/2%/1gm
15gm
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Medical Condition(s) for which Melacare may be prescribed

Acne
Acute Myeloid Leukemia

Side effects of Melacare

   Most Common : Headache, fever, skin dryness, bone pain, nausea/vomiting, rash, itching, increased sweating, visual disturbances, hair loss, skin changes and bone inflammation.

   Body as a Whole : Uneasiness, shivering, bleeding, infections, swelling in the extremities, chest discomfort, increased and decreased weight, injection site reactions, loss of appetite, muscle pain, flank pain, fluid imbalance, pallor, lymph disorders, acidity and chills.

   Respiratory : Upper respiratory tract disorders, difficulty in breathing, respiratory insufficiency, pneumonia, wheezing, lung infection/swelling and asthma.

   ENT : Ear pain and hearing loss.

   Gastrointestinal : GI hemorrhage, abdominal pain, diarrhea, constipation, indigestion, abdominal distention, liver inflammation, ulcer and unspecified liver disorder.

   Heart : Abnormal heart rate, flushing, low/high blood pressure, vein inflammation, heart failure, heart attack, enlarged heart, heart murmur and stroke.

   Central Nervous System : Dizziness, tingling, anxiety, sleeplessness, depression, confusion, agitation, hallucinations, abnormal gait, convulsions, coma, CNS depression, speech disorder, encephalopathy, facial paralysis, tremor, leg weakness, unconsciousness, dementia, memory loss, drowsiness and slow speech.

   Genitourinary : Kidney impairment, painful urination, urinary frequency and enlarged prostate.

   Miscellaneous : Skin lesions.

Dosage & When it is to be taken (Indications)

PO- The recommended dose is 45 mg/m2/day administered as two evenly divided doses.
Topical- 0.05% apply a thin layer of cream over the affected area.

How to use Melacare?

It comes as a capsule to take by mouth, with or without food.
Topical- It comes as a liquid, cream and gel to apply topically.

When is Melacare not to be taken? (Contraindications)

Hypersensitivity.

Warnings and Precautions for Melacare

Caution should be exercised in patients with history of blood cholesterol, liver or heart disease, abnormally high white blood cell count, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
It may cause dizziness or severe headache, do not drive a car or operate machinery while taking this medication.
Monitor pregnancy tests, blood clotting factors, blood cholesterol and triglyceride levels, liver function and white blood cell counts regularly while taking this medication.
It should not be used in children less than 1 year old.
Topical :
Wash your hands thoroughly after applying this medication.
Avoid exposure to sunlight.
Keep away from eyes, mouth, angles of nose, mucous membranes or open wounds.

Other Precautions for Melacare

Avoid excess dosage.

Storage Conditions for Melacare

Store at 15° to 30°C. Keep the container tightly closed at room temperature and out of the reach of children.


Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.



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