• Central Nervous System:
Headache and dizziness.
• Miscellaneous: Fever, chills, allergic reactions, gastrointestinal disturbances, disturbances in liver enzyme levels, redness of skin and blood disorders.
• Potentially Fatal: Stevens-Johnson syndrome and toxic epidermal necrolysis.
Adult: IV- Prophylaxis of Gram-positive infection in high-risk patients undergoing surgery: 400 mg as a single dose at induction of anesth.
CAPD(continuous ambulatory peritoneal dialysis)-associated peritonitis- If the patient is febrile, an initial loading dose of 400 mg may be given.
Teicoplanin is added to the dialysis solution at a concentration of 20 mg/litre; dose is added into each bag of solution in the first week, followed by alternate bags in the second week and then in the overnight dwell bag in the third week.
IV/IM- Serious Gram-positive infections Initial: 6 mg/kg on the 1st day, then 3 mg/kg/day. Severe infection: 6 mg/kg 12 hourly for the 1st 3 doses, then 6 mg/kg/day.
It comes as a solution for injection, to be administered by a healthcare provider into the vein. /
• Caution should be exercised in patients with history of preexisting kidney impairment, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Monitor blood counts, liver function regularly.
Avoid excess dosage.
Store it at controlled room temperature (below 25°C). Reconstituted solutions may be stored for 24 hours at 2-8°C.