Aacef S (250 mg) is a cephalosporin antibiotic, prescribed for certain bacterial infections such as gonorrhea, pelvic inflammatory disease, middle ear infection, meningitis (inflammation of the covering of the brain), and infections of the lungs, ears, skin, urinary tract, blood, bones and joints and typhoid. 

Drug information on Aacef S (250 mg) (Ceftriaxone) from Blue Cross Laboratories Ltd.

Aacef S (250 mg)

  Injection
Blue Cross Laboratories Ltd.
Generic : Ceftriaxone
 39.00
250mg/125mg/1vial
1vial
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Medical Condition(s) for which Aacef S (250 mg) may be prescribed

Infective Endocarditis
Lyme Disease
Meningitis
Otitis Media
Pneumonia
Shigellosis
Syphilis
Typhoid and Paratyphoid Enteric Fevers

Side effects of Aacef S (250 mg)

  Central Nervous System: Dizziness, Headache.

  Gastrointestinal: Diarrhea, nausea and vomiting.

  Blood: High concentration of eosinophils, platelet counts in the blood, decrease in white blood cells, low prothrombin levels, bleeding.

  Lab tests: Increase in liver enzyme, elevated BUN (Blood urea, nitrogen).

  Local: Indurations/tightness/warmth.

  Genitourinary: Vaginal inflammation.

  Miscellaneous: Fatal ceftriaxone-calcium precipitates in lung and kidneys of neonates.

Dosage & When it is to be taken (Indications)

Middle ear infection: Children - IM A single dose of 50 mg/kg (max, 1 gram) is recommended.
Meningitis in children: Children - IV: Recommended initial dose is 100 mg/kg (max, 4 gram), followed by 100 mg/kg/day (max, 4 gram/day) for 7 to 14 days.
Skin or Skin Structure Infections: Children - IV/IM: Recommended daily dosage is 50 to 75 mg/kg once a day or in equally divided doses twice daily (max, 2 gram/day).
Surgical Prophylaxis: Adults - IV: 1 gram as a single dose 30 min to 2 hours before surgery.
Uncomplicated Gonococcal Infections: Adults - IM: 250 mg as single dose.
Miscellaneous Infections: Adults - IV: Usual adult daily dosage is 1 to 2 g once a day or in equally divided doses twice daily, depending on the type and severity of infection (max, 4 gram/day).
Children- IV: Recommended daily dose is 50 to 75 mg/kg IV once a day or in divided doses every 12 h (max, 2 gram/day). IV/IM: Recommended daily dose is 50 to 75 mg/kg IV/IM in divided doses every 12 h (max, 2 gram/day).
Acute Bacterial Otitis Media Persistent/Treatment Failure: Children - IM/IV 50 mg/kg/ IM or IV (not to exceed 1 gram) daily for 3 days.
Pelvic Inflammatory Disease (mild to moderate): Adults - IM 250 mg given IM as a single dose with doxycycline 100 mg orally twice daily for 14 days, with or without metronidazole 500 mg orally twice daily for 14 days.
Uncomplicated Gonococcal Infections: Adults - IM 125 mg given IM as a single dose.
Typhoid:Adult- IV: 4gm/day for 2 days, followed by 2g/day. Child- 75mg/day for 2 days.

How to use Aacef S (250 mg)?

It comes as a solution for injected to be administered intravenously (into a vein) or intramuscularly (into a muscle), by a healthcare provider.

When is Aacef S (250 mg) not to be taken? (Contraindications)

Hypersensitivity to cephalosporins; neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hours of ceftriaxone administration due to risk of calcium-ceftriaxone precipitate formation in neonates.

Warnings and Precautions for Aacef S (250 mg)

Caution should be exercised in patients with history of penicillin allergy; severe renal impairment; pregnancy and lactation; problem with digestive system, especially colitis (inflammation of the large intestine), malnutrition (you do not eat or cannot digest the nutrients needed for good health), super infection.

• Be sure for the full course of treatment. If you do not, the medicine may not clear up your infection completely.

Other Precautions for Aacef S (250 mg)

Avoid long-term or repeated use, otherwise it will secondary infection.

Storage Conditions for Aacef S (250 mg)

Injection: Store below 25°C. Store it at room temperature and keep away from children.



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