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Zoledronic Acid

Latest prescription information about Zoledronic Acid. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Zoledronic Acid
Pronunciation : ZOE-le-DRON-ik AS-id
Trade Name(s): 
India- Aclasta, Blaztere Inj Vial, Cytozol Vial, Zifonate Vial, Zobone, Zolasta Vial, Zoldonat Vial, Zoldria Vial, Zoldro Vial, Zoledron Vial, Zoltero Vial, Zometa Vial, Zyfoss Inj.
International- Reclast, Zometa, Aclasta.
Why it is prescribed (Indications) : 
This medication is a bisphosphonate, primarily used for prevention and treatment of osteoporosis in men and postmenopausal women. It is also used for Paget's disease and osteoporosis caused by steroid treatment. It reduces the amount of calcium released from the bones into the blood.

When it is not to be taken (Contraindications): 


Contraindicated in patients who are allergic to this drug, people with paralysis condition and during pregnancy and lactation.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
IV- The recommended dose is 4mg/100m, over 15min; may be repeated after a week.
How it should be taken : 
It comes as a solution for injection, administered by a healthcare provider.
Special Instruction : 
* Caution should be exercised in patients with history of kidney disease, dehydration problem, asthma, during pregnancy and breastfeeding.
* Drink adequate fluids to avoid dehydration.
* Do routine oral examination in patients at risk of osteonecrosis of the jaws.
* Monitor serum electrolytes, calcium, phosphate and magnesium.
* Withhold treatment if there is worsening of kidney function.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Most Common- Fever, muscle pain, headache, joint pain, pain in extremity.
Blood - Anemia.
Metabolic - Dehydration and loss of appetite.
Central Nervous System- Dizziness.
Heart- Atrial fibrillation, vascular disorders and high blood pressure.
Gastrointestinal- Nausea, diarrhea, vomiting and abdominal pain.
Musculoskeletal- Shoulder pain, neck pain and muscle spasms.
General - Fever, influenza-like illness, fatigue, chills, weakness, peripheral edema, uneasiness and chest pain.
Other Precautions : 
* Maintain proper level of calcium and Vitamin D. Patient may develop kidney impairment.
Storage Conditions : 
Injection: Store at 15-30°C (59-86°F). Normally stored by healthcare providers.

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