Vincristine - Drug Information

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General Information on Vincristine

Generic Name : Vincristine

Pronunciation : vin-KRIS-teen

Latest prescription information about Vincristine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Vincristine

India : 

International : 

Oncovin, Vincasar

Why is Vincristine Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for certain types of cancer such as leukemia, Hodgkin disease, and non-Hodgkin lymphomas.  It slows or stops the growth of cancer cells in the body.

When should Vincristine not to be taken? (Contraindications)

Contraindicated in patients with demyelinating form of Charcot-Marie-Tooth syndrome (an inherited disorder of nerves).

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Vincristine?

Adult- PO- The recommended dose is 1.4-1.5 mg/m2 once weekly. Max: 2 mg/week.

How should Vincristine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Vincristine?

• Caution should be exercised in patients with history of infection, decrease in blood counts, blood problems due to chemotherapy, liver disease, muscle problems, nerve disease, any allergy, during pregnancy and breastfeeding.
• It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Vincristine?

   Most Common : Hair loss.
   Gastrointestinal : Constipation, abdominal cramps, weight loss, nausea, vomiting, mouth ulceration, diarrhea, intestinal necrosis and loss of appetite.
   Genitourinary : Painful urination, bed-wetting and increased urination.
   Heart : High/low blood pressure and heart attack.
   Blood : Bone marrow depression.
   Miscellaneous : Fever and headache.

What are the other precautions for Vincristine?

Avoid excess dosage.

What are the storage conditions of Vincristine?

Store it in refrigerator (2°-8°C), protect from light.

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