Vinblastine - Drug Information

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General Information on Vinblastine

Generic Name : Vinblastine

Pronunciation : vin blas' teen

Latest prescription information about Vinblastine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Vinblastine

India : 

International : 

Velban

Why is Vinblastine Prescribed? (Indications)

This medication is an anti-microtubule agent, prescribed for Hodgkin's lymphoma, lung cancer, breast cancer, head and neck cancer, and testicular cancer.  It slows or stops the growth of cancer cells in the body.

When should Vinblastine not to be taken? (Contraindications)

Contraindicated in patients with abnormal decrease in white blood cells, bacterial infections and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Vinblastine?

Adult- IV- Initial: The recommended dose is 3.7 mg/m2, body surface area (bsa). It may be increased if needed. Maximum: 18.5 mg/m2/week.

How should Vinblastine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Vinblastine?

Caution should be exercised in patients with history of infections, bone marrow problems, low blood cell counts, liver problems, undergoing radiation therapy, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may reduce platelet counts; avoid injury of bruising.
Avoid contact with eyes and mucus membranes.
It may cause severe side effects such as sudden breathing problem, tightness in the lungs, sore throat, fever, chills, and sore mouth. If it is so consult with your doctor.

What are the side effects of Vinblastine?

   Blood : Anemia and abnormal decrease in white blood cells.
   Skin : Hair loss and sensitivity to light.
   Gastrointestinal : Constipation, loss of appetite, nausea, vomiting, abdominal pain, inflammation pharynx, mouth, diarrhea, stomach bleeding, peptic ulcer and rectal bleeding.
   Central Nervous System : Numbness, inflammation of nerves, mental depression, headache and convulsions.
   Heart : High blood pressure, heart attack, chest pain and abnormalities of ECG.
   Miscellaneous : Uneasiness, bone pain, weakness, pain in tumor-containing tissue, dizziness and jaw pain.

What are the other precautions for Vinblastine?

Avoid excess dosage.

What are the storage conditions of Vinblastine?

Store it in refrigerator (2 to 8C).

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