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Venlafaxine

Latest prescription information about Venlafaxine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Venlafaxine
Pronunciation : ven' la fax een
Therapeutic Classification : psychotherapeutics
Trade Name(s): 
India- Dalium Tab, Envelaf Xr-Cap, Faxiven-Xr Tab, Flavix Tab, Flavix Xr-Tab, Sentosa Er-Tab, Sentosa Tab, Venaxin-Sr -Tab, Venaxin-Sr Tab, Vendep Xr Er-Cap, Venfax-Pr Er-Cap, Veniz-Xr Er-Cap, Venjoy-Xr Extentab, Venla Cap, Venla Suscap, Venlift Od Cap, Venlift Od Tab, Venlift Tab, Venlor Tab , Venlor-Xr Cap, Ven-Od Cap, Venrea Ercap, Vexor Extentab.
Internationl-Effexor.
Why it is prescribed (Indications) : 
This medication is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI), prescribed for depression, generalized anxiety disorder, social anxiety disorder, and panic disorder.

When it is not to be taken (Contraindications): 


Contraindicated in patients who are taking MAOIs or who have taken MAOIs within 14 days, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
For depression- Initial: 75 mg/day in 2-3 divided doses, increase slowly if needed. Max: 375 mg/day.
For anxiety Extended release- Initial: 75 mg once daily, may increase slowly if needed. Max: 225 mg/day.
For panic disorder- 37.5 mg once daily for 1st 7 days, may increase slowly if needed. Max: 225 mg/day.
How it should be taken : 
It comes as a tablet or extended-release capsule to take by mouth. Take tablet 2times/day and extended-release capsule once daily in the morning or evening with food.
Special Instruction : 
*It may cause moderate to severe liver or kidney problems. Conditions which may be worsened by increase in heart rate.
* Caution should be exercised in patients with history of heart attack, bleeding disorder, epilepsy, hypomania or mania, elderly, during pregnancy.
* Monitor blood pressure, serum cholesterol regularly.
* Monitor closely during early therapy until depression improves due to increased risk of suicide.
* Discontinue if seizure develops or increase in seizure frequency.
Side Effects : 
Heart- Widening of blood vessels,high blood pressure, palpitations, fast heart beat, low blood pressure, deep vein blood clot, ECG abnormalities (eg, QT prolongation), irregular heart beat.
Central Nervous System- Headache, drowsiness, dizziness, sleeplessness, nervousness, weakness, anxiety, tremor, abnormal dreams, agitation, depression, increased muscle tightness, tingling, twitching, abnormal thinking, confusion, loss of memory, impaired coordination and balance, involuntary movements, shock-like electrical sensations.
Skin- Sweating, rash, itching, redness of the skin, toxic epidermal blistering.
Eye and ENT- Throat inflammation, abnormal vision, dilation of pupil, taste perversion, sudden eye pressure, eye bleeding.
Gastrointestinal- Nausea, dry mouth, loss of appetite, constipation, abdominal pain, diarrhea, vomiting, indigestion, flatulence, eructation, increased appetite,bleeding.
Genitourinary- Abnormal ejaculation, impotence, decreased sexual activity, impaired urination, orgasm disturbance, urinary frequency, albumin in urine, painful menstruation, weak urination, vaginal inflammation, urinary retention.
Blood-Discoloration of skin, decrease in white blood cell, decrease in platelets, and neutrophils.
Liver- Liver function abnormalities, liver damage, necrosis, or failure, and fatty liver.
Metabolic- Weight loss, edema, weight gain
Respiratory- Inflammation of bronchus, cough increased, difficulty in breathing, interstitial lung disease.
Miscellaneous- Yawning, chills, flu-like syndrome, infection, accidental injury, chest pain, trauma, joint pain, fever, neck pain, chest pain, birth defect, bleeding, increased prolactin, night sweats, high concentration of eosinophils, kidney failure.
Other Precautions : 
*Avoid abrupt withdrawal. Withdraw gradually over at least 1 to 2 week.
Storage Conditions : 
Oral: Store below 30°C. Store it in an airtight container and keep away from children.

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