Generic Name : Vandetanib Pronunciation : van-DET-a-nib
International- Caprelsa. Why it is prescribed (Indications) :
This medication is a kinase inhibitor, prescribed for medullary thyroid cancer. It blocks the action of an abnormal protein that signals cancer cells to multiply. When it is not to be taken (Contraindications): Contraindicated in patients with congenital long QT syndrome.
Dosage & When it is to be taken :
PO- The recommended daily dose is 300 mg. How it should be taken :
It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of heart disease, irregular heartbeat, heart attack, liver or kidney impairment, lung or breathing problems, bleeding episodes, high blood pressure, abnormal blood electrolyte, underactive thyroid, skin disease, diarrhea, decrease in white blood cell levels and platelet levels; who are taking other medications, any allergy, during pregnancy and breastfeeding.
* It may cause tiredness, weakness, or blurred vision, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may reduce platelet counts; avoid injury or bruising.
* Avoid exposure to sunlight.
* Monitor ECGs, liver, thyroid, and kidney function; blood pressure, blood sugar, blood electrolyte levels and complete blood cell counts regularly while taking this medication. Side Effects :
Most Common - Diarrhea, rash, acne, nausea, high blood pressure, headache, fatigue, decreased appetite, and abdominal pain.
Skin - Dry Skin, photosensitivity, itching.
Gastrointestinal - Vomiting, indigestion, decreased weight.
Central Nervous System - Weakness, sleeplessness, depression, tiredness, weakness.
Serious Effects- QT prolongation.
* Avoid excess dosage. Storage Conditions :
Stored it at room temperature (25°C).
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