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Valrubicin

Latest prescription information about Valrubicin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Valrubicin
Pronunciation : val ROO bi sin
Trade Name(s): 
International- Valstar.
Why it is prescribed (Indications) : 
This medication is a chemotherapy agent, prescribed for bladder cancer.  It works by preventing the cancer cell from reproducing, which results in death of the cancer cell.
When it is not to be taken (Contraindications): Contraindicated in patients with concurrent urinary tract infections, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
IV- The recommended dose is 800 mg, once a week for six weeks.
How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of bone marrow problems, kidney disease, severe bladder irritation, who are taking other medications, any allergy, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid contact with skin or eyes.
* Men should avoid sex.
* Monitor complete blood cell counts, bladder exams, and urine tests regularly while taking this medication.
Side Effects : 
Most Common - Urinary frequency, painful urination, urinary urgency, bladder spasm, blood in urine, bladder pain, urinary incontinence, bladder inflammation, night time urination, injection site burning, urethral pain, pelvic pain.
Body as a Whole - Abdominal pain, weakness, back pain, chest pain, fever, headache, uneasiness.
Heart - Dilatation.
Gastrointestinal - Diarrhea, flatulence, nausea, vomiting.
Blood - Anemia.
Metabolic - Low blood sugar and swelling in the extremities.
Musculoskeletal - Muscle pain.
Central Nervous System - Dizziness.
Respiratory - Pneumonia.
Skin - Rash.
Genitourinary - Urinary Retention, urinary tract infection.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store the medication as directed by your physician.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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