Trimethadione - Drug Information

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General Information on Trimethadione

Generic Name : Trimethadione

Pronunciation : trye- meth- a- dye'- one

Latest prescription information about Trimethadione. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y46.6 | Therapeutic Classification : Anticonvulsants

Trade Names/Brand Names of Trimethadione

International- Troxidone, Tridione.

Why is Trimethadione Prescribed? (Indications)

This medication is an anticonvulsant, prescribed for seizure disorders.  It works by reducing abnormal electrical activity in the brain.

When should Trimethadione not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Trimethadione?

Adult - The recommended dose is 0.9-2.4 grams daily in 3 or 4 equally divided doses (i.e., 300-600 mg 3 or 4 times daily).
Children- Usually 0.3-0.9 gram daily in 3 or 4 equally divided doses.

How should Trimethadione be taken?

It comes as a tablet, capsule, and liquid to take by mouth on an empty stomach.

What are the warnings and precautions for Trimethadione?

Caution should be exercised in patients with history of kidney, liver disease, blood disorders, eye problems, allergies, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid exposure to sunlight.

What are the side effects of Trimethadione?

  Gastrointestinal: Nausea, vomiting, abdominal pain, gastric distress.
  Central Nervous System: Drowsiness, fatigue, uneasiness, sleeplessness, vertigo, headache, tingling, precipitation of grand mal seizures, increased irritability, personality changes.
  Blood: Bleeding gums, epistaxis, retinal and petechial bleeding, vaginal bleeding, anemia, decrease in white blood cells, platelets; eosinophilia, and bone marrow depression.
  Skin: Skin rash, skin inflammation, and redness.
  Miscellaneous: Hiccups, loss of appetite, weight loss, hair loss, changes in blood pressure, albumin in urine, sensitivity to light, and double vision.

What are the other precautions for Trimethadione?

Avoid excess dosage.

What are the storage conditions of Trimethadione?

Store it at room temperature, away from excess heat and moisture.

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