Trazodone - Drug Information

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General Information on Trazodone

Generic Name : Trazodone

Pronunciation : traz' oh done

Latest prescription information about Trazodone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.2 | Therapeutic Classification : Psychotherapeutics

Why is Trazodone Prescribed? (Indications)

This medication is an antidepressant, prescribed for depression and anxiety.  It increases the amounts of certain natural substances that are needed for mental balance.

When should Trazodone not to be taken? (Contraindications)

Contraindicated in patients who have taken linezolid, methylene blue, or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days, and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Trazodone?

Adult: PO- Depression Initial: 150 mg/day, increase slowly, up to 300-400 mg/day if needed. Max: 600 mg/day in divided doses.
Anxiety Initial: 75 mg/day, up to 300 mg/day if needed.

How should Trazodone be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Trazodone?

Caution should be exercised in patients with history of depression, mental problems, suicidal thoughts, alcoholism, irregular heartbeat, low blood pressure, cancer, heart attack, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid alcohol consumption.
It should not be used in children.
Patient may develop with increased risk of suicidal thoughts; watch them carefully.
Patient may develop with increased risk of Serotonin Syndrome with the following symptoms: restlessness, diarrhea, fast heart beat, incoordination, nausea, vomiting. If it is so consult with your healthcare provider.

What are the side effects of Trazodone?

   Allergic reactions : Rash, itching, hives, swelling, blurred vision, constipation and dry mouth.
   Heart : High blood pressure, shortness of breath, fainting, fast heart rate and palpitations.
   Central Nervous System : Anger, confusion, decreased concentration, disorientation, dizziness/lightheadedness, drowsiness, excitement, fatigue, headache, sleeplessness, memory loss, nervousness, incoordination, tingling and tremors.
   Gastrointestinal : Abdominal disorder, bad taste in mouth, diarrhea, nausea and vomiting.
   Musculoskeletal : Muscle/joint pain.
   Miscellaneous: Decreased libido, decreased appetite, redness/tired/itching of eyes, uneasiness, nose block, abnormal dreams, sweating, ringing in the ear and weight gain/loss.

What are the other precautions for Trazodone?

Avoid excess dosage.

What are the storage conditions of Trazodone?

Store it at room temperature (30C).


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner. ♦ Safety Labeling Changes Approved By FDA

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Manoli 

Regarding your trazodone 150 mg tab. I have to take 2 tabs at night. I CHOKE on them. Why are they not coated or something else. They are just pressed and the moment I put them in my mouth they start to dissolve. They taste terrible and leave an aftertaste. Is there any you can suggest besides applesauce.

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