Tranylcypromine - Drug Information

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General Information on Tranylcypromine

Generic Name : Tranylcypromine

Pronunciation : tran ill sip' roe meen

Latest prescription information about Tranylcypromine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.1 | Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Tranylcypromine

International- Parnate.

Why is Tranylcypromine Prescribed? (Indications)

This medication is a monoamine oxidase (MAO) inhibitor, prescribed for depression. It increases the amounts of certain natural substances that are needed for mental balance.

When should Tranylcypromine not to be taken? (Contraindications)

Contraindicated in patients with brain defects, heart disease, kidney tumors, co-administered with MAO inhibitors, bupropion, serotonin reuptake inhibitors (SSRIs) or selective norepinephrine reuptake inhibitors (SNRIs), sympathomimetics, buspirone, meperidine, dextromethorphan, undergoing elective surgery and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Tranylcypromine?

Dose is based on patient’s condition. The usual effective dosage is 30 mg per day in divided doses.

How should Tranylcypromine be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Tranylcypromine?

• Caution should be exercised in patients with history of high blood pressure, headache, adrenal tumor, stroke, heart, blood vessel or liver disease, anxiety, agitation, diabetes, seizures, kidney or thyroid disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
• It may cause drowsiness, dizziness or fainting, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
• Avoid taking food item which contain tyramine; otherwise it may cause severe high blood pressure while taking this medication.
• Avoid taking caffeinated beverages while taking this medication.
• Avoid alcohol consumption.
• It may cause increased risk of suicidal thoughts in children and teenagers; watch them carefully.

What are the side effects of Tranylcypromine?

•   Central Nervous System : Anxiety, agitation, weakness, drowsiness, dizziness and dry mouth.
•   Gastrointestinal : Nausea, diarrhea, abdominal pain and constipation.
•   Miscellaneous : Fast heart rate, loss of appetite, swelling in the extremities, palpitations, blurred vision, chills and impotence.

What are the other precautions for Tranylcypromine?

Avoid exposure to sunlight; it may cause sunburn easily.
Monitor blood pressure regularly while taking this medication.

What are the storage conditions of Tranylcypromine?

Store it at room temperature and keep away from light.


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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